https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Trends in sudden infant death syndrome in Australia from 1980-2002 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5022 Wed 22 Mar 2023 16:11:49 AEDT ]]> Independent external validation of predictive models for urinary dysfunction following external beam radiotherapy of the prostate: issues in model development and reporting https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25021 0.6. Shrinkage was required for all predictive models' coefficients ranging from -0.309 (prediction probability was inverse to observed proportion) to 0.823. Predictive models which include baseline symptoms as a feature produced the highest discrimination. Two models produced a predicted probability of 0 and 1 for all patients. Conclusions: Predictive models vary in performance and transferability illustrating the need for improvements in model development and reporting. Several models showed reasonable potential but efforts should be increased to improve performance. Baseline symptoms should always be considered as potential features for predictive models.]]> Wed 19 Jan 2022 15:16:35 AEDT ]]> Impact of treatment planning and delivery factors on gastrointestinal toxicity: an analysis of data from the RADAR prostate radiotherapy trial https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:16753 Wed 11 Apr 2018 15:29:36 AEST ]]> Technical quality assurance during the TROG 03.04 RADAR prostate radiotherapy trial: are the results reflected in observed toxicity rates? https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:26791 Sat 24 Mar 2018 07:36:30 AEDT ]]> Dosimetry, clinical factors and medication intake influencing urinary symptoms after prostate radiotherapy: an analysis of data from the RADAR prostate radiotherapy trial https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:22835 1 timepoints. Associations at a single timepoint were found for cerebrovascular condition, ECOG status and non-steroidal anti-inflammatory drug intake. Peak incidence analysis shows the impact of baseline, bowel and cerebrovascular condition and smoking status. Conclusions: The prevalence and incidence analysis provide a complementary view for urinary symptom prediction. Sustained impacts across time points were found for several factors while some associations were not repeated at different time points suggesting poorer or transient impact.]]> Sat 24 Mar 2018 07:16:08 AEDT ]]> Urinary symptoms following external beam radiotherapy of the prostate: Dose-symptom correlates with multiple-event and event-count models https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:22558 Sat 24 Mar 2018 07:14:46 AEDT ]]> Statistical-learning strategies generate only modestly performing predictive models for urinary symptoms following external beam radiotherapy of the prostate: a comparison of conventional and machine-learning methods https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24849 0.6 while all haematuria endpoints and longitudinal incontinence models produced AUROC<0.6. Conclusions: Logistic regression and MARS were most likely to be the best-performing strategy for the prediction of urinary symptoms with elastic-net and random forest producing competitive results. The predictive power of the models was modest and endpoint-dependent. New features, including spatial dose maps, may be necessary to achieve better models.]]> Sat 24 Mar 2018 07:11:24 AEDT ]]> Association between measures of treatment quality and disease progression in prostate cancer radiotherapy: An exploratory analysis from the TROG 03.04 RADAR trial https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42619 Mon 04 Sep 2023 13:58:46 AEST ]]>